Gene information
Official symbol TLR4
Official full name toll like receptor 4
Gene type protein-coding gene
Chromosome9q33.1
Alias symbolhToll; CD284; TLR-4; ARMD10
Gene familyCD molecules; Toll like receptors
Resources
Entrez Gene 7099
HGNC HGNC:11850
Ensembl ENSG00000136869
Vega OTTHUMG00000021046
UCSC uc004bjz.5
GO terms: 246 records
GO Description Category LogP Number of genes Detail
GO:0001540 amyloid-beta binding GO Molecular Functions -10.7345181 13 More
GO:0001775 cell activation GO Biological Processes -43.3738118 71 More
GO:0001818 negative regulation of cytokine production GO Biological Processes -48.9957481 97 More
GO:0001819 positive regulation of cytokine production GO Biological Processes -44.1872667 64 More
GO:0001894 tissue homeostasis GO Biological Processes -10.3152206 20 More
GO:0001934 positive regulation of protein phosphorylation GO Biological Processes -52.8272623 84 More
GO:0002221 pattern recognition receptor signaling pathway GO Biological Processes -6.97185167 18 More
GO:0002224 toll-like receptor signaling pathway GO Biological Processes -4.97797298 7 More
GO:0002237 response to molecule of bacterial origin GO Biological Processes -48.4964960 93 More
GO:0002250 adaptive immune response GO Biological Processes -8.22919489 29 More
GO:0002252 immune effector process GO Biological Processes -24.2648770 43 More
GO:0002263 cell activation involved in immune response GO Biological Processes -10.3401505 18 More
GO:0002274 myeloid leukocyte activation GO Biological Processes -20.6988408 25 More
GO:0002285 lymphocyte activation involved in immune response GO Biological Processes -7.04246662 12 More
GO:0002312 B cell activation involved in immune response GO Biological Processes -4.27715369 6 More
GO:0002366 leukocyte activation involved in immune response GO Biological Processes -10.4998832 18 More
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO Biological Processes -11.9339394 22 More
GO:0002683 negative regulation of immune system process GO Biological Processes -26.6415063 77 More
GO:0002694 regulation of leukocyte activation GO Biological Processes -32.0887020 60 More
GO:0002696 positive regulation of leukocyte activation GO Biological Processes -27.9249645 47 More
GO:0002697 regulation of immune effector process GO Biological Processes -33.2683521 48 More
GO:0002699 positive regulation of immune effector process GO Biological Processes -18.3926498 29 More
GO:0002700 regulation of production of molecular mediator of immune response GO Biological Processes -19.7615296 26 More
GO:0002702 positive regulation of production of molecular mediator of immune response GO Biological Processes -12.4206918 17 More
GO:0002703 regulation of leukocyte mediated immunity GO Biological Processes -18.0432682 27 More
GO:0002718 regulation of cytokine production involved in immune response GO Biological Processes -15.9157324 18 More
GO:0002720 positive regulation of cytokine production involved in immune response GO Biological Processes -8.11676834 10 More
GO:0002755 MyD88-dependent toll-like receptor signaling pathway GO Biological Processes -3.92689699 4 More
GO:0002761 regulation of myeloid leukocyte differentiation GO Biological Processes -12.4818724 17 More
GO:0002762 negative regulation of myeloid leukocyte differentiation GO Biological Processes -4.32673439 6 More
GO:0002764 immune response-regulating signaling pathway GO Biological Processes -3.80325753 14 More
GO:0002831 regulation of response to biotic stimulus GO Biological Processes -10.931136 25 More
GO:0002833 positive regulation of response to biotic stimulus GO Biological Processes -5.95822718 13 More
GO:0005769 early endosome GO Cellular Components -6.25251045 19 More
GO:0006468 protein phosphorylation GO Biological Processes -5.36604576 56 More
GO:0006909 phagocytosis GO Biological Processes -7.82039874 17 More
GO:0006954 inflammatory response GO Biological Processes -86.5569367 100 More
GO:0007586 digestion GO Biological Processes -7.00342423 19 More
GO:0008283 cell population proliferation GO Biological Processes -17.2298624 68 More
GO:0008289 lipid binding GO Molecular Functions -15.8223476 88 More
GO:0009595 detection of biotic stimulus GO Biological Processes -6.46280795 7 More
GO:0009611 response to wounding GO Biological Processes -63.1714102 77 More
GO:0009612 response to mechanical stimulus GO Biological Processes -18.7627330 44 More
GO:0009617 response to bacterium GO Biological Processes -52.1760880 83 More
GO:0009620 response to fungus GO Biological Processes -9.57465113 11 More
GO:0009897 external side of plasma membrane GO Cellular Components -28.0033937 46 More
GO:0010001 glial cell differentiation GO Biological Processes -13.0211768 33 More
GO:0010008 endosome membrane GO Cellular Components -3.11007663 16 More
GO:0010543 regulation of platelet activation GO Biological Processes -12.2843439 12 More
GO:0010935 regulation of macrophage cytokine production GO Biological Processes -5.69256069 5 More
GO:0010942 positive regulation of cell death GO Biological Processes -48.7037743 123 More
GO:0014002 astrocyte development GO Biological Processes -7.75588867 8 More
GO:0014910 regulation of smooth muscle cell migration GO Biological Processes -16.4082106 27 More
GO:0014911 positive regulation of smooth muscle cell migration GO Biological Processes -11.1068742 16 More
GO:0016798 hydrolase activity, acting on glycosyl bonds GO Molecular Functions -2.52984204 7 More
GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds GO Molecular Functions -2.53594783 4 More
GO:0021782 glial cell development GO Biological Processes -9.97103962 23 More
GO:0022600 digestive system process GO Biological Processes -8.16734280 17 More
GO:0030335 positive regulation of cell migration GO Biological Processes -66.7331035 139 More
GO:0030888 regulation of B cell proliferation GO Biological Processes -7.97568198 10 More
GO:0030890 positive regulation of B cell proliferation GO Biological Processes -8.50618951 9 More
GO:0031252 cell leading edge GO Cellular Components -1.97716247 28 More
GO:0031334 positive regulation of protein-containing complex assembly GO Biological Processes -8.84926570 16 More
GO:0031347 regulation of defense response GO Biological Processes -64.5971043 148 More
GO:0031349 positive regulation of defense response GO Biological Processes -32.1301903 71 More
GO:0031663 lipopolysaccharide-mediated signaling pathway GO Biological Processes -14.0408172 12 More
GO:0032103 positive regulation of response to external stimulus GO Biological Processes -58.7273809 118 More
GO:0032479 regulation of type I interferon production GO Biological Processes -2.18052786 4 More
GO:0032496 response to lipopolysaccharide GO Biological Processes -45.257773 87 More
GO:0032642 regulation of chemokine production GO Biological Processes -25.2850711 37 More
GO:0032648 regulation of interferon-beta production GO Biological Processes -2.10510364 3 More
GO:0032649 regulation of interferon-gamma production GO Biological Processes -12.4733429 27 More
GO:0032651 regulation of interleukin-1 beta production GO Biological Processes -19.7300517 34 More
GO:0032652 regulation of interleukin-1 production GO Biological Processes -24.2088254 41 More
GO:0032653 regulation of interleukin-10 production GO Biological Processes -10.1959901 18 More
GO:0032655 regulation of interleukin-12 production GO Biological Processes -15.9447313 16 More
GO:0032660 regulation of interleukin-17 production GO Biological Processes -6.79373102 8 More
GO:0032675 regulation of interleukin-6 production GO Biological Processes -28.2553997 51 More
GO:0032677 regulation of interleukin-8 production GO Biological Processes -20.0046302 33 More
GO:0032680 regulation of tumor necrosis factor production GO Biological Processes -32.0729913 56 More
GO:0032689 negative regulation of interferon-gamma production GO Biological Processes -6.05054543 11 More
GO:0032720 negative regulation of tumor necrosis factor production GO Biological Processes -18.6356508 28 More
GO:0032722 positive regulation of chemokine production GO Biological Processes -22.4503100 21 More
GO:0032729 positive regulation of interferon-gamma production GO Biological Processes -7.58110530 10 More
GO:0032731 positive regulation of interleukin-1 beta production GO Biological Processes -11.8061175 13 More
GO:0032732 positive regulation of interleukin-1 production GO Biological Processes -14.7376831 16 More
GO:0032755 positive regulation of interleukin-6 production GO Biological Processes -18.6559032 31 More
GO:0032757 positive regulation of interleukin-8 production GO Biological Processes -14.6396218 15 More
GO:0032760 positive regulation of tumor necrosis factor production GO Biological Processes -21.1788990 23 More
GO:0032872 regulation of stress-activated MAPK cascade GO Biological Processes -11.6818048 20 More
GO:0032874 positive regulation of stress-activated MAPK cascade GO Biological Processes -9.63549885 15 More
GO:0032943 mononuclear cell proliferation GO Biological Processes -3.89391544 7 More
GO:0032944 regulation of mononuclear cell proliferation GO Biological Processes -24.6915018 34 More
GO:0032946 positive regulation of mononuclear cell proliferation GO Biological Processes -20.2231223 25 More
GO:0033218 amide binding GO Molecular Functions -9.50305686 47 More
GO:0033674 positive regulation of kinase activity GO Biological Processes -29.8538991 87 More
GO:0034341 response to interferon-gamma GO Biological Processes -10.8524889 26 More
GO:0038187 pattern recognition receptor activity GO Molecular Functions -6.19476810 6 More
GO:0040017 positive regulation of locomotion GO Biological Processes -69.9490345 147 More
GO:0042060 wound healing GO Biological Processes -56.2139708 65 More
GO:0042063 gliogenesis GO Biological Processes -20.3412228 47 More
GO:0042113 B cell activation GO Biological Processes -5.56585733 12 More
GO:0042116 macrophage activation GO Biological Processes -15.3664951 15 More
GO:0042277 peptide binding GO Molecular Functions -10.2245210 22 More
GO:0042742 defense response to bacterium GO Biological Processes -25.9215771 41 More
GO:0043030 regulation of macrophage activation GO Biological Processes -14.6396218 15 More
GO:0043032 positive regulation of macrophage activation GO Biological Processes -14.1432953 16 More
GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling GO Biological Processes -8.71585030 18 More
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling GO Biological Processes -8.04470175 15 More
GO:0043235 receptor complex GO Cellular Components -19.4198369 40 More
GO:0043254 regulation of protein-containing complex assembly GO Biological Processes -7.63830100 21 More
GO:0043405 regulation of MAP kinase activity GO Biological Processes -18.9267681 42 More
GO:0043406 positive regulation of MAP kinase activity GO Biological Processes -13.8261343 18 More
GO:0043408 regulation of MAPK cascade GO Biological Processes -57.2547066 142 More
GO:0043409 negative regulation of MAPK cascade GO Biological Processes -13.5471736 35 More
GO:0043410 positive regulation of MAPK cascade GO Biological Processes -49.4744054 112 More
GO:0043549 regulation of kinase activity GO Biological Processes -36.8507249 123 More
GO:0044089 positive regulation of cellular component biogenesis GO Biological Processes -10.7794496 56 More
GO:0045088 regulation of innate immune response GO Biological Processes -6.98001665 16 More
GO:0045089 positive regulation of innate immune response GO Biological Processes -3.90916833 9 More
GO:0045321 leukocyte activation GO Biological Processes -25.4958219 48 More
GO:0045346 regulation of MHC class II biosynthetic process GO Biological Processes -9.43730348 7 More
GO:0045348 positive regulation of MHC class II biosynthetic process GO Biological Processes -9.26986898 6 More
GO:0045428 regulation of nitric oxide biosynthetic process GO Biological Processes -19.2075726 26 More
GO:0045429 positive regulation of nitric oxide biosynthetic process GO Biological Processes -13.6962150 18 More
GO:0045596 negative regulation of cell differentiation GO Biological Processes -26.9785067 101 More
GO:0045637 regulation of myeloid cell differentiation GO Biological Processes -9.39364926 18 More
GO:0045638 negative regulation of myeloid cell differentiation GO Biological Processes -3.67865682 7 More
GO:0045670 regulation of osteoclast differentiation GO Biological Processes -10.2566667 12 More
GO:0045859 regulation of protein kinase activity GO Biological Processes -34.3615088 109 More
GO:0045860 positive regulation of protein kinase activity GO Biological Processes -29.3929160 47 More
GO:0046328 regulation of JNK cascade GO Biological Processes -6.26985667 21 More
GO:0046330 positive regulation of JNK cascade GO Biological Processes -6.26494407 10 More
GO:0046649 lymphocyte activation GO Biological Processes -10.1732143 26 More
GO:0046651 lymphocyte proliferation GO Biological Processes -3.08061793 6 More
GO:0046982 protein heterodimerization activity GO Molecular Functions -2.81006698 12 More
GO:0048471 perinuclear region of cytoplasm GO Cellular Components -8.50169248 66 More
GO:0048660 regulation of smooth muscle cell proliferation GO Biological Processes -48.6624498 69 More
GO:0048661 positive regulation of smooth muscle cell proliferation GO Biological Processes -29.0732096 40 More
GO:0048708 astrocyte differentiation GO Biological Processes -6.43952602 8 More
GO:0048871 multicellular organismal homeostasis GO Biological Processes -14.5562171 53 More
GO:0050135 NAD(P)+ nucleosidase activity GO Molecular Functions -3.41433421 5 More
GO:0050670 regulation of lymphocyte proliferation GO Biological Processes -22.6006415 32 More
GO:0050671 positive regulation of lymphocyte proliferation GO Biological Processes -19.1485102 24 More
GO:0050708 regulation of protein secretion GO Biological Processes -30.3716714 63 More
GO:0050714 positive regulation of protein secretion GO Biological Processes -15.7339081 32 More
GO:0050727 regulation of inflammatory response GO Biological Processes -68.5964592 121 More
GO:0050729 positive regulation of inflammatory response GO Biological Processes -38.1621935 57 More
GO:0050778 positive regulation of immune response GO Biological Processes -17.2528761 40 More
GO:0050829 defense response to Gram-negative bacterium GO Biological Processes -15.0142277 17 More
GO:0050864 regulation of B cell activation GO Biological Processes -7.98662389 16 More
GO:0050865 regulation of cell activation GO Biological Processes -40.6877761 71 More
GO:0050867 positive regulation of cell activation GO Biological Processes -31.2431659 51 More
GO:0050871 positive regulation of B cell activation GO Biological Processes -8.77049404 15 More
GO:0051046 regulation of secretion GO Biological Processes -54.0079540 130 More
GO:0051047 positive regulation of secretion GO Biological Processes -32.2282376 71 More
GO:0051090 regulation of DNA-binding transcription factor activity GO Biological Processes -25.8933515 78 More
GO:0051091 positive regulation of DNA-binding transcription factor activity GO Biological Processes -17.7436786 49 More
GO:0051092 positive regulation of NF-kappaB transcription factor activity GO Biological Processes -14.8614421 21 More
GO:0051222 positive regulation of protein transport GO Biological Processes -13.8994291 46 More
GO:0051223 regulation of protein transport GO Biological Processes -25.2801266 81 More
GO:0051249 regulation of lymphocyte activation GO Biological Processes -22.6120519 46 More
GO:0051251 positive regulation of lymphocyte activation GO Biological Processes -20.2181987 37 More
GO:0051272 positive regulation of cellular component movement GO Biological Processes -66.5150412 143 More
GO:0051347 positive regulation of transferase activity GO Biological Processes -26.6059528 90 More
GO:0051606 detection of stimulus GO Biological Processes -2.56190637 17 More
GO:0051769 regulation of nitric-oxide synthase biosynthetic process GO Biological Processes -8.50460337 7 More
GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process GO Biological Processes -7.53000143 6 More
GO:0055094 response to lipoprotein particle GO Biological Processes -14.9317808 12 More
GO:0060249 anatomical structure homeostasis GO Biological Processes -12.3640817 24 More
GO:0060759 regulation of response to cytokine stimulus GO Biological Processes -13.7003447 35 More
GO:0060760 positive regulation of response to cytokine stimulus GO Biological Processes -4.64741860 7 More
GO:0060907 positive regulation of macrophage cytokine production GO Biological Processes -3.47400635 3 More
GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response GO Biological Processes -3.92081595 4 More
GO:0061809 NAD+ nucleotidase, cyclic ADP-ribose generating GO Molecular Functions -3.41433421 5 More
GO:0062207 regulation of pattern recognition receptor signaling pathway GO Biological Processes -5.69211704 17 More
GO:0070201 regulation of establishment of protein localization GO Biological Processes -24.4831554 82 More
GO:0070302 regulation of stress-activated protein kinase signaling cascade GO Biological Processes -11.5600448 20 More
GO:0070304 positive regulation of stress-activated protein kinase signaling cascade GO Biological Processes -9.54226030 15 More
GO:0070372 regulation of ERK1 and ERK2 cascade GO Biological Processes -38.4320790 79 More
GO:0070374 positive regulation of ERK1 and ERK2 cascade GO Biological Processes -34.9831828 64 More
GO:0070661 leukocyte proliferation GO Biological Processes -8.25401122 12 More
GO:0070663 regulation of leukocyte proliferation GO Biological Processes -26.8242532 37 More
GO:0070665 positive regulation of leukocyte proliferation GO Biological Processes -21.5362473 27 More
GO:0070848 response to growth factor GO Biological Processes -40.6139195 102 More
GO:0071214 cellular response to abiotic stimulus GO Biological Processes -11.2775864 23 More
GO:0071216 cellular response to biotic stimulus GO Biological Processes -28.1549742 59 More
GO:0071219 cellular response to molecule of bacterial origin GO Biological Processes -28.3848077 56 More
GO:0071222 cellular response to lipopolysaccharide GO Biological Processes -26.0381191 52 More
GO:0071260 cellular response to mechanical stimulus GO Biological Processes -11.7214175 13 More
GO:0071345 cellular response to cytokine stimulus GO Biological Processes -39.647808 70 More
GO:0071346 cellular response to interferon-gamma GO Biological Processes -8.94844866 13 More
GO:0071363 cellular response to growth factor stimulus GO Biological Processes -39.8883675 98 More
GO:0071396 cellular response to lipid GO Biological Processes -37.0669488 98 More
GO:0071402 cellular response to lipoprotein particle stimulus GO Biological Processes -16.0665913 13 More
GO:0071417 cellular response to organonitrogen compound GO Biological Processes -26.3253267 90 More
GO:0071496 cellular response to external stimulus GO Biological Processes -17.0078490 52 More
GO:0071900 regulation of protein serine/threonine kinase activity GO Biological Processes -19.5794055 63 More
GO:0071902 positive regulation of protein serine/threonine kinase activity GO Biological Processes -13.5008002 23 More
GO:0080135 regulation of cellular response to stress GO Biological Processes -19.0128542 89 More
GO:0080164 regulation of nitric oxide metabolic process GO Biological Processes -19.7892071 27 More
GO:0090594 inflammatory response to wounding GO Biological Processes -8.11856573 7 More
GO:0098543 detection of other organism GO Biological Processes -4.09160195 4 More
GO:0098552 side of membrane GO Cellular Components -22.4625650 48 More
GO:0098581 detection of external biotic stimulus GO Biological Processes -6.40916397 6 More
GO:0104004 cellular response to environmental stimulus GO Biological Processes -11.2775864 23 More
GO:0120161 regulation of cold-induced thermogenesis GO Biological Processes -19.1025541 38 More
GO:0120163 negative regulation of cold-induced thermogenesis GO Biological Processes -2.63486357 4 More
GO:0140052 cellular response to oxidised low-density lipoprotein particle stimulus GO Biological Processes -5.39331932 6 More
GO:1900015 regulation of cytokine production involved in inflammatory response GO Biological Processes -18.8349263 16 More
GO:1900017 positive regulation of cytokine production involved in inflammatory response GO Biological Processes -9.17938755 7 More
GO:1900225 regulation of NLRP3 inflammasome complex assembly GO Biological Processes -4.09160195 4 More
GO:1900407 regulation of cellular response to oxidative stress GO Biological Processes -21.4526227 33 More
GO:1901214 regulation of neuron death GO Biological Processes -23.5458880 37 More
GO:1901216 positive regulation of neuron death GO Biological Processes -5.62852599 9 More
GO:1901222 regulation of NIK/NF-kappaB signaling GO Biological Processes -7.00394995 9 More
GO:1901224 positive regulation of NIK/NF-kappaB signaling GO Biological Processes -6.64954322 9 More
GO:1901652 response to peptide GO Biological Processes -34.9047734 89 More
GO:1901653 cellular response to peptide GO Biological Processes -21.5212108 58 More
GO:1901699 cellular response to nitrogen compound GO Biological Processes -26.9091664 96 More
GO:1902105 regulation of leukocyte differentiation GO Biological Processes -18.8286876 32 More
GO:1902106 negative regulation of leukocyte differentiation GO Biological Processes -7.27922558 19 More
GO:1902532 negative regulation of intracellular signal transduction GO Biological Processes -29.4927428 92 More
GO:1902882 regulation of response to oxidative stress GO Biological Processes -20.0046302 33 More
GO:1903201 regulation of oxidative stress-induced cell death GO Biological Processes -18.4601079 28 More
GO:1903203 regulation of oxidative stress-induced neuron death GO Biological Processes -4.46557398 5 More
GO:1903426 regulation of reactive oxygen species biosynthetic process GO Biological Processes -7.23199669 13 More
GO:1903428 positive regulation of reactive oxygen species biosynthetic process GO Biological Processes -4.65238816 7 More
GO:1903530 regulation of secretion by cell GO Biological Processes -45.6472055 114 More
GO:1903532 positive regulation of secretion by cell GO Biological Processes -27.9542102 63 More
GO:1903555 regulation of tumor necrosis factor superfamily cytokine production GO Biological Processes -32.3948799 57 More
GO:1903556 negative regulation of tumor necrosis factor superfamily cytokine production GO Biological Processes -18.2876323 28 More
GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production GO Biological Processes -20.7768498 23 More
GO:1903706 regulation of hemopoiesis GO Biological Processes -16.2759166 33 More
GO:1903707 negative regulation of hemopoiesis GO Biological Processes -7.72888419 20 More
GO:1903829 positive regulation of protein localization GO Biological Processes -12.9651258 57 More
GO:1904407 positive regulation of nitric oxide metabolic process GO Biological Processes -14.4967625 19 More
GO:1904464 regulation of matrix metallopeptidase secretion GO Biological Processes -13.0040256 7 More
GO:1904645 response to amyloid-beta GO Biological Processes -11.2505232 12 More
GO:1904646 cellular response to amyloid-beta GO Biological Processes -6.94782947 8 More
GO:1904951 positive regulation of establishment of protein localization GO Biological Processes -13.0308630 46 More
GO:2000147 positive regulation of cell motility GO Biological Processes -67.8620360 143 More
GO:2000341 regulation of chemokine (C-X-C motif) ligand 2 production GO Biological Processes -5.55591541 5 More
GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production GO Biological Processes -7.34622031 5 More
GO:2000377 regulation of reactive oxygen species metabolic process GO Biological Processes -19.1025541 38 More
GO:2000379 positive regulation of reactive oxygen species metabolic process GO Biological Processes -15.0445998 16 More
KEGG pathways: 29 records
KEGG Description Category LogP Number of genes Detail
hsa04064 NF-kappa B signaling pathway KEGG Pathway -10.0294934 14 More
hsa04066 HIF-1 signaling pathway KEGG Pathway -20.6790877 23 More
hsa04151 PI3K-Akt signaling pathway KEGG Pathway -29.3006421 73 More
hsa04217 Necroptosis KEGG Pathway -8.49909048 15 More
hsa04613 Neutrophil extracellular trap formation KEGG Pathway -12.8071279 20 More
hsa04620 Toll-like receptor signaling pathway KEGG Pathway -11.1460554 15 More
hsa04621 NOD-like receptor signaling pathway KEGG Pathway -7.63493695 15 More
hsa04936 Alcoholic liver disease KEGG Pathway -13.3477535 19 More
hsa05130 Pathogenic Escherichia coli infection KEGG Pathway -9.84822677 18 More
hsa05131 Shigellosis KEGG Pathway -5.26807538 14 More
hsa05132 Salmonella infection KEGG Pathway -7.42305681 17 More
hsa05133 Pertussis KEGG Pathway -13.2270528 15 More
hsa05134 Legionellosis KEGG Pathway -13.8022551 14 More
hsa05135 Yersinia infection KEGG Pathway -7.02427022 12 More
hsa05140 Leishmaniasis KEGG Pathway -12.4439861 14 More
hsa05142 Chagas disease KEGG Pathway -21.3868632 23 More
hsa05144 Malaria KEGG Pathway -31.5561809 24 More
hsa05145 Toxoplasmosis KEGG Pathway -13.6215025 17 More
hsa05146 Amoebiasis KEGG Pathway -14.8474637 18 More
hsa05152 Tuberculosis KEGG Pathway -14.5221547 22 More
hsa05161 Hepatitis B KEGG Pathway -5.78517620 12 More
hsa05162 Measles KEGG Pathway -4.80674483 10 More
hsa05164 Influenza A KEGG Pathway -16.0885267 23 More
hsa05170 Human immunodeficiency virus 1 infection KEGG Pathway -2.98955463 9 More
hsa05171 Coronavirus disease - COVID-19 KEGG Pathway -24.8179886 34 More
hsa05205 Proteoglycans in cancer KEGG Pathway -18.5545131 27 More
hsa05321 Inflammatory bowel disease KEGG Pathway -16.3800424 16 More
hsa05323 Rheumatoid arthritis KEGG Pathway -22.3868189 23 More
hsa05417 Lipid and atherosclerosis KEGG Pathway -33.3876857 40 More
Drug-Gene interaction
view
Related drugs: 11 records
Drug name Interaction type Source PMID View
alcohol NCI 11431739 view
eritoran TdgClinicalTrialTTD 1682058517803912 view
eritoran tetrasodium antagonist ChemblInteractions view
infliximab NCI 12847679 view
methotrexate PharmGKB 20136356 view
nelfinavir NCI 15388451 view
pravastatin PharmGKB 12742999 view
resatorvid antagonist TdgClinicalTrialTTD view
ritonavir NCI 15388451 view
saquinavir NCI 15388451 view
tacrolimus PharmGKB 24820765 view
Related studies: 14 records
Molecular factor Omics type Application Objective MI type Reference
TLR4 transcriptomics acute myocardial infarction[diagnosis] acute myocardial infarction Satoh M et al. Int J Cardiol. 2006
TLR4 transcriptomics heart failure[prognosis (bad)] acute myocardial infarction Satoh M et al. Int J Cardiol. 2006
TLR4 transcriptomics acute ST elevation myocardial infarction[diagnosis] acute ST elevation myocardial infarction Ishikawa Y et al. Clin Sci (Lond). 2008
TLR4 transcriptomics adverse events[prognosis (bad)] acute ST elevation myocardial infarction Ishikawa Y et al. Clin Sci (Lond). 2008
TLR4 transcriptomics acute myocardial infarction[diagnosis] acute myocardial infarction Lima-Neto LG et al. J Biol Regul Homeost Agents. 2014
TLR4 transcriptomics atrial fibrillation[prognosis (bad)] acute myocardial infarction Zhang P et al. Int Heart J. 2018
NM_138554.5:c.896A>G genomics myocardial infarction[diagnosis] myocardial infarction Holloway JW et al. Pharmacogenet Genomics. 2005
NM_138554.5:c.[896A>G;1196C>T] genomics myocardial infarction[diagnosis] myocardial infarction Edfeldt K et al. Eur Heart J. 2004
Toll-like receptor 4 proteomics acute ST elevation myocardial infarction[diagnosis] acute ST elevation myocardial infarction Ishikawa Y et al. Clin Sci (Lond). 2008
Toll-like receptor 4 proteomics adverse events[prognosis (bad)] acute ST elevation myocardial infarction Ishikawa Y et al. Clin Sci (Lond). 2008
Toll-like receptor 4 proteomics adverse events[prognosis (bad)] acute ST elevation myocardial infarction Sheu JJ et al. Int Heart J. 2008
Toll-like receptor 4 proteomics acute myocardial infarction[diagnosis] acute myocardial infarction Kashiwagi M et al. Atherosclerosis. 2012
Toll-like receptor 4 proteomics acute myocardial infarction[diagnosis] acute myocardial infarction Hally KE et al. Thromb Res. 2017
NG_011475.2:g.8374A>G genomics myocardial infarction[diagnosis] myocardial infarction Enquobahrie DA et al. Am J Cardiol. 2008
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